It could be. Turkish is a gender-neutral language. O stands for he/she/it.
So does this mean the same as the English translation, how is she emotionally, how is she doing? How is she at this specific moment? Or is it more like "what's she like? "what kind of person is she in general?"
The lesson only allows 'How is she?' as correct, but 'How is he?' and 'How is it?' is also correct.
''Ne kadar'' means ''how much'' for askin to price -It's a pattern sentence- ''Nasıl'' means ''how?'' in ''Nasılsın'' (how are you?), ''how was your day'' (Günün Nasıl idi/Nasıldı), ''How is the weather'' (Hava nasıl?)
*''Ne'' means ''what'' but it also using in sentence ''ne kadar''(how much), ''Ne zaman?'' (literally means:What time, When), ''Ne yedin?'' (what did you eat?)