There isn't if you debate only the words themselves. It can alter the meaning of the sentence though, but the same way as in English, for example: This is a boy - To jest chłopiec. This is the boy - To jest ten chłopiec - As if you wanted to point out and say "it's him!" - I just roughly translated it into This is that boy. Literally. I guess that is how it works. I might not be correct for I am native and there might be something not actually ringing the bell which should, but in general answer is: no, no, no.
The instrumental case is a grammatical case used to indicate that a noun is the instrument or means by or with which the subject achieves or accomplishes an action.
There are seven cases: nominative (mianownik), genitive (dopełniacz), dative (celownik), accusative (biernik), instrumental (narzędnik), locative (miejscownik), and vocative (wołacz).
All this is from Wikipedia