Translation:The girls play basketball and tennis.
Well, more like 'into', because it's used with accusative, but yes. You use «игра́ть в» + Accusative when you play sports or other games, and «играть на» + Prepositional when you play musical instruments.
Indeed, this is an exception. In foreign loanwords, «е» after consonants is often pronounced as if it's written «э».
See my answer here for more examples: https://www.duolingo.com/comment/11578282$comment_id=11579418
Basketball is definitely played in Russia (and, I believe, most post-USSR countries).
Football is popular too, but I'm not sure if we mean the same thing by football. If you use the word 'soccer' for something different than 'football', than you can assume your kind of football is not known in Russia. ^^'
BTW, I found this comment by @littleblueduck in the Ukrainian course funny (and true): https://www.duolingo.com/comment/12687653
It can mean either. Maybe «девочки» refers to more than one group of girls, some of which play tennis and some basketball. Maybe «играют» describes their habits and not the activity in this exact moment. Both meanings are possible in Russian.