"Er ist rot mit weißen Blumen."
"Er" can refer to a masculine noun and be better represented by "it" in English. "Er" could be referring to "Rock" which is the masculine noun for "skirt".
But, if you use your imagination with the English sentence as it stands...
- "Daddy, have you seen my teddy bear, Mr. Snuggles?"
- "No sweetheart, what does he look like?"
- "He is red with white flowers."
Completely plausible to come across that sentence in a kids book.
Hope that helps!
If you're asking about the German phrase: yes, there surely is since 'er' can refer to any grammatically masculine object, e.g.: 'Sein Anzug ist schön. Er ist rot mit weißen Blumen'. As far as the English phrase is concerned, you may need some imagination, perhaps talking about some guy at a mardi gras or Halloween celebration ;-)