Yes, there is a difference in meaning.
"Are those programs interesting?" - you already know that there are programs. You are pointing to a specific group of programs and are asking whether they are interesting.
"Are those interesting programs?" - you may not know whether they are programs. You are pointing to something and asking whether that group of things is a group of interesting programs.
I think the Hungarian version of the second question would be Azok érdekes műsorok?
When I went to the Szeged nyari jatekok I alway bought the program ant then in those times that program ,schedule,the Hungarians called ''musor''Now I can't go to these wonderful summer festival because the tickets were sold on the net and you can get them no more So I think the musor is a program not a show.
Duolingo's programming doesn't always make the sentences adhere to the topic. Rather, it looks at what words you've learnt, and when you know all the words to form a particular sentence, that sentence will be taught, even if it doesn't contain the focus element of the lesson. You're probably learning the word műsor in the "Inessive" lesson somewhere, so this sentence gets filed in there as well.