No, that would not make sense in Hebrew. The difference can be seen in another verb, to give (נתן / לתת):
- למי אנחנו נותנים? = to whom are we giving?
- את מי אנחנו נותנים? = whom are we giving?
The meanings are very different. With helping (עזר / לעזור), you always need to use ל־ (to).