I realize this is an old question, but in case anyone's wondering the same thing these days: I'm just a learner too, but from what I've learned, "it" is not neutral in Hebrew, as it is in English. Everything has a grammatical female or male gender. (It's like that in many other languages.) Therefore, "הוא" and "היא" can both translate to "it", as well as to "he" and "she", respectively. Of course, "Without her I have nothing." is a correct answer, but "Without it I have nothing." is equally correct. Again, I'm learning. If I'm incorrect, please correct me.