It depends what you mean. Generally, the topic (temat; what you are talking about) is placed at the beginning and comment (remat; what is being said about the topic) is put at the end. So that the beginning introduces the subject and what you want to say about it is placed at the end.
If the verb is core information, it should be placed at the end. Generally, in Polish sentence accent falls on second-to-last syllable of the sentence and it is a neutral position.
would Nic nie wiem o was be acceptable--as in the last question: Nie nie wiesz o nas--?
Acceptable, but I'd recommend "Nic o was nie wiem" as the best option. As well as "Nic o nas nie wiesz".