"Your profession is hard."

Translation: Profesia voastră este grea.

[mcgrpd10]

In this case I can't use "e" instead of "este"?

[dilez]

They are always interchangeable. If it wasn't accepted, there was either something else wrong with the answer or a problem on duolingo's part.

[Lng52-._]

Instead of formal "voastră", Duo also accepts "ta" (Feb. 10,2020).

[Mediterran18]

What is wrong with "Meseria ta este grea" ?