yes, not sure if duolingo would accept it though

Not really, but "avec qui est ce que je parle" is counted as correct.

^^

"Est-ce que je parle..." can be translated "Is it that I am talking.."

Two finite verbs in the same sentence cannot be. To use 'suis' you could maybe choose for the present participle of parler: Je suis en train de parler avec qui? So, in this case 'am' is translated with 'suis en train de' followed by the verb. At least, that's how I've understood this part of the French grammar.

here you speak, he hear, only.

I think "je dis" is "I say" instead of "I speak" ("je parle") you might want to double check that though

qui is who/whom and quoi is what