"Poslední láhev vína jsme vypili před dvěma hodinami."

Translation: We drank the last bottle of wine two hours ago.

[Krmelka001]

we finished the last bottle of wine two hours ago?

[LukasBlech]

It should have been added. "Finished" means "vypít", "dojíst", etc when we are talking about food.

[VladaFu]

I'd say that it is closer to dopít instead.

[dpushnitsyn]

we had drunk the last bottle of wine two hours ago - could it be accepted?

[LukasBlech]

No. When you specific the time in the past, you have to use past simple tense.

[dpushnitsyn]

I am not a native English speaker, so I am not 100% sure. But here what I have found: https://dictionary.cambridge.org/grammar/british-grammar/ago . So basically, it is possible to use past perfect tense when we specify time. However, yes I made here a mistake with the word "ago". It would be better to use here "before".
But this was not my point. My point here was that "vypili" is a perfective verb: http://www.locallingo.com/czech/grammar/verbal_aspect.html .
So I assume that "We had drunk the last bottle of wine two hours before" may be accepted.