"The girls are wearing dresses."
Translation:Die Mädchen tragen Kleider.
No, it wouldn't. While once Kleider was used to mean clothing, it is not longer used that way in everyday conversations. You can find these meaning in some sayings, e.g. "Kleider machen Leute" meaning clothes determine what kind of person you are. Or in old texts, e.g. "Des Kaisers neue Kleider" The emperors new clothes.