"Can we resolve this or not?"
Translation:¿Podemos resolver esto o no?
Yep, gender is the issue here. For anyone that wants a deep dive, see this link. You'll get into all of the demonstrative pronouns and adjectives (which are effectively identical - it's the accent marks, which aren't really important anymore), when to use either and why and learn a bit of current usage vs. the outdated info. I think the key here is to just learn the masculine and feminine forms (singular and plural) and employ them as appropriate. Good luck.
(I see that this comment was made 4 years ago.)
That is not exactly true, Mitty (your nickname?). Esto is a demonstrative pronoun, but este can be a demonstrative pronoun or a demonstrative adjective. This site might help - https://studyspanish.com/grammar/lessons/demonstratives
Anyone can be wrong, and that certainly includes me. I believe that when someone posts a comment, we should check it's accuracy before accepting it as being correct. (This goes for politics, too!)
You may have to exercise some faith here since I don't have any official sources of information for you. I personally think initially you should take lo/le/la (in various instances) to mean he/she/it and esto/esta/este to mean this. Since there are very few times (actually can't remember any examples of it!) you're better off (or at least I was) not confusing the two since if you use esto/esta/este at least 90/95% of the time (I say that presumptuously) you'll have the right translation.
Spanish uses 'u' instead of 'o' when the word that follow starts with an 'oh' sound. Here's an example: "Sea por un razón u otro" - "Be it for one reason or another", instead of "Sea por un razón o otro". This is the rule to avoid what they call 'cacophony', which are certain combinations of sounds that are difficult to pronounce (the double 'oh' sound in this case). There is a similar rule for changing 'y' to 'e' when followed by an 'ee' sound: 'él es bueno e inteligente'. And similarly, it is why we use masculine articles with some feminine nouns that start with 'a', for example, we say 'el agua' instead of 'la agua', and 'el arma' instead of 'la arma'. But in the plural we go back to the proper feminine articles 'las aguas' and 'las armas' because the double 'a' cacophony doesn't exist. Bueno suerte todos.