"Where's your house?"
吗 is basically used for closed questions that require a "yes or no" answer. 你累了吗, Are you tired? 你喜欢吗, Do you like it?
We wouldn't use 吗 if asking about time and place as open ended questions as the answer could be 那里, over there; or 明天早上, tomorrow morning. Unless of course you asked something like 妈妈在这里吗, Is mom here? (again this is a yes/no question even though its related to a place).