"Oh, poor man!"
Translation:¡Ay, pobre hombre!
Some adjectives change meaning when they are before the noun. In this case, pobre before the noun means unfortunate while it means impoverished after the noun. Both are synonyms of poor due to it having multiple definitions (like a lot of English words) so it can be a bit confusing.
In this case pobre connotes the sympathy we feel and not his financial status.
According to my Spanish dic. humano is human wich can also be a female wich is not in the original statement.