The word यह transforms to इस when there is a postposition like में, पर, के साथ etc. (Same with वह to उस, ये to इन and वे to उन.) The appropriate example would be इस सेब के साथ नाश्ता करो (Have breakfast with this apple).
House (the actual building) would be makaan, while home is ghar. If you are referring to the literal house, they are interchangable, but you wouldn't describe the larger area where someone lives as their house.