Ugh, Tasche was always 'bag' when I was learning it then they throw this curveball.
I wouldn't try looking for reasons... Or you will have to find a reason for Mädchen and Kind to be neuter!
Mädchen is neuter because is Mad + chen and all words with suffix "chen" become neuter. Same for equivalent suffix "lein" e.g. Fräulein also neuter. Kind is neuter for the same reason as child in english
Ah...but das Gepäck (luggage) is neuter. Best not to get into the "everything in this category is this" mindset.