This might sound a little bit unsatisfying, but there aren't that many rules.
When having a specific ending and gender, the word is likely to have a specific plural ending:
a, o, u, au often - but not always - make a "I-Umlautierung" and turn into ä, ö, ü, äu.
Abbreviations form the plural either depending on the word or with -s
der Lastkraftwagen, der LKW
die Lastkraftwagen, die LKW oder die LKWs
I cannot think of any appart from these and don't try to guess unless you have to: It is to easy to fail! the best solution is to learn - for every noun - gender (der, die oder das) and the plural form.
die Maus, die Mäuse
die Laus, die Läuse
das Haus, die Häuser
No, Because most plurals in German have the as "Die"
Its one of the main ways to recognize whether something is plural or not.
An example of this is the two sentences
"Das Mädchen isst" And "Die Mädchen essen"
Mädchen is both singular and plural, so you have to use the other words in the sentence to figure out if it's plural or not.