Is this like asking what one is doing right now, or what one works?
The former. The latter would be तुम क्या करते/करती हो? (What do you do?).
That said, you can also use the present continuous sentence to ask about someone's job by saying तुम आज कल क्या कर रही हो? (What are you doing these days?)
Do you have to add something to change the tone of it? Or is it based on... well, tone?