"signore" can means:
ladies (le signore) | And still is not so correct, as "signora" stands in italian for "mrs", usually for ladies peolple'd say "signorine" So in the end one use "le signore" for old ladies or married women.
sir (il signore)
definitely "signore" do not translate to women (le donne).
Hope really it was clear (and also that I answered to what you asked, cause I'm not sure..)