"Are you coming from the city?"
Translation:Venitis ab urbe?
While not necessary, the enclitic "-ne" is often used at the beginning of the first word of a "yes/no" question. So, the preferred answer should be "venitisne ab urbe" or "venisne ab urbe" (the verb also often came first in these questions).
There is no indication of whether this is meant to be a singular or plural "you".