Yes, there's a difference. No, it's not interchangeable.
Going to another place (in general).
One piece of travel (going from one place to another) usually a long distance. No return implied.
The act of going to another place (often for a short period of time) and returning.
Well, actually, back in the day -- you know when people used to "make journeys" (i.e., in the 1500's) -- a "journey" was LITERALLY a one day's trip, not a trip around the world, mind ye. So seeing it as a long trip is a bit anachronistic. Just throwing it out there for all ye definition wizards.