So then how do you say just "I'm fed up" (without the "with it")?
You can say the same way.
Or possibly - j’en ai ras le bol. I think French requires the ‘en’ though English doesn’t necessarily require ‘with it’.
Does "J'ai marre" mean I'm fed up, and the "en" is used to refer to the download from the previous sentence?
I agree "i'm fed up" implies with something so "with it" isn't needed.
"....is taking too long" would be much more common.