"È grande la differenza?"

Translation: Is the difference big?

[Archangelica]

what's wrong with "is it a big difference" ??

[Thoughtdiva]

I agree this would be a good English equivalent.

[jgbachand]

In English, we also speak of a "great" difference. "Is the difference great?" is the way I translated it, and it was not accepted.

[Thoughtdiva]

I think that's fine too :)