It is a very literal translation, and would be understood. It might even have a strange grammatical example on file somewhere showing it to be "correct". But it is not a phrase that would generally be uttered by a native speaker.
I am a native English speaker and I am happy to tell you that "What you say makes no sense" is the most natural-sounding way to express this. "That which you say makes no sense" is correct, but sounds absurd.