"Do you know where my watch is?"
Translation:Weet je waar mijn horloge is?
No, that doesn't really work because of the word order. "Weet je waar mijn horloge zit?" would be a good sentence. Though i don't think i would ever ask it that way. 'Zitten' means something like 'is placed' in this sentence. Someone could answer 'Hij/Het zit in één van je zakken', it's in one of your pockets.
The grammar section has this: The verb ‘zitten’ (= to sit) is used to describe the location of:
an object or a person that is located inside of something else, such as a building, a room or a box.