Translation:Ella lo necesita a él.
Ella necesita de él.
Ella lo necesita a él.
Is 'él' the direct object in both sentences? In the second one, is 'él' a direct AND indirect object?
"Él" is the D.O., but "ella necesita de él" is not a sentence I would ever say, maybe in some other areas they do, so I hope someone can help you with that! In my opinion it is just a D.O., but I am not sure...