"What is your profession?"
Translation:Sizin mesleğiniz nedir?
It is the same -DIr suffix you see popping up for facts. It is commonly used for questions like this :)
ne senin mesleğin? why incorrect in turkish the word question comes at first and end of the sentence?
That doesn't really make sense in most contexts in Turkish. The subject of the sentence "your profession" must come first. :)