Destinations (objects of verbs of motion) must be in the oblique case, but they do not require Position in Hindi. वह मेरे कमरे जा रहा है - He is going to my room. .
In English, generally preposition 'to' not used with destination like 'home' , 'school' , 'room', 'office' if it is not a 'Proper noun' . Please understand, Grammar English is filled with demons called 'Exceptions' and there are 'Exceptions of Exceptions.' : )